Labels:text | screenshot | black and white | black | monochrome OCR: abolite T4 is deiodinated either to the active me own as or to a biologically inactive metabolite k of T4 5' reverse T3 (rT3) (Fig. 15.10). Three types a widely deiodinase have been described. Type I i ble for distributed selenoprotein that is respons duced generation of the majority of T3. It has n d is activity in starvation or severe illness ar resent in inhibited by propylthiouracil. Type II is F local the brain and pituitary. It is important fo creased generation of T3 in these areas and has i dividuals, activity in hypothyroidism. In healthy in Lin T4 is converted equally to T3 and rT3, bu ty of acute severely ill people suffering from a varie T3 is and chronic non thyroidal illnesses, less late, T3 andproduced and high levels of rT3 accumu dinated or rT3 are usually subsequently fur ...
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